MACS® Cell Separation – Select the best technology for your cell isolation

We offer cell isolation methods tailored to your target cell needs. Our unique cell separation portfolio combines our proven magnetic cell isolation technology with exciting new options, providing for workflows across basic and clinical research. Whether isolating cells in small-scale experiments or in high-throughput industrial settings – we offer manual, semi-automated, automated, and robotic integration solutions to meet your specific research demands.

• The mosted cited cell separation technology in over 25,000 publications
• Fast, easy, and gentle to cells using MACS® MicroBeads
• From manual cell isolation experiments to fully automated high-throughput projects
• Cell isolation straight from whole blood, buffy coat, LRSC, or leukopak®

The basics of magnetic cell separation with MACS® Technology

Additional information:

Due to the strong amplification of the magnetic field, minimal labeling of cells with nano-sized superparamagnetic beads suffices to retain target cells in the column. Labeled cells hover between the ferromagnetic spheres while unlabeled cells pass freely through the column. The columns can be washed thoroughly to remove cell debris and undesired cells. MACS Columns thus provide gentle conditions for cell separation. Besides this, MACS Cell Separation is easy to accomplish and compatible with any downstream application, including cell sorting, flow cytometry analysis, cell culture, functional assays, and molecular analysis.

Cells move freely between the spheres inside the column and are only retained by magnetic forces.

Amplification of the magnetic force within the MACS Column allows cell separation with minimal labeling. Without the use of a MACS Column, extensive labeling or large beads are needed for an adequate magnetic retention (A). Only the amplification of the magnetic force by MACS Columns ensures effective cell retention with minimal labeling using small beads (B).